Fig. 4

Frequency of CD4+ CD25+ FoxP3+ cells in blood and secondary lymphoid tissue in response to short-term and long-term fingolimod (FTY720) treatment post-brain ischaemia in young mice (t = 10 days). Two-sided, independent-samples t tests investigated differences between two groups (* = p < 0.05, ** = p < 0.01, *** = p < 0.001 as compared to saline). One-way analysis of variance (ANOVA) tests with post hoc Tukey’s multiple comparisons were performed to investigate differences between three or more groups (# = p < 0.05, ## = p < 0.01, ### = p < 0.001 as compared to saline). Number of mice per group is shown in parentheses on x-axis. Box-and-whisker plots exhibit 10–90 percentiles