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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: TGR5 activation attenuates neuroinflammation via Pellino3 inhibition of caspase-8/NLRP3 after middle cerebral artery occlusion in rats

Fig. 1

TGR5 and Pellino3 levels after middle cerebral artery occlusion (MCAO). a Representative Western blot images and quantitative analyses of time courses of TGR5 and Pellino3 proteins from right hemisphere after MCAO. n = 6 per group, *P < 0.05 vs. Sham group. b Double immunofluorescence staining for TGR5 (red) in microglia (Iba-1, green), neuron (green) in the penumbra following MCAO. n = 4 per group. c The relative fluorescent intensity of TGR5 in microglia and neurons, n = 4 for each group, *P < 0.05 vs. Sham. Bars represent mean ± SD. Scale bar, 50 μm. Iba-1, ionized calcium binding adaptor molecule 1

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