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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: TGR5 activation attenuates neuroinflammation via Pellino3 inhibition of caspase-8/NLRP3 after middle cerebral artery occlusion in rats

Fig. 2

Expression of TGR5 after middle cerebral artery occlusion (MCAO). a, b Double immunofluorescence staining and relative fluorescent intensity of TGR5 (red) in GFAP (green) in the penumbra following MCAO. n = 4 per group, *P < 0.05 vs. Sham. Scale bar, 50 μm. c, d Flow cytometry showing that TGR5 accumulates to higher levels in CD11b+CD45intermediate microglia and CD11b+CD45high macrophages at 24 h after MCAO. n = 6 for each group, *P < 0.05 vs. Sham. GFAP, glial fibrillary acidic protein

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