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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Sirtuin 3 protects against anesthesia/surgery-induced cognitive decline in aged mice by suppressing hippocampal neuroinflammation

Fig. 7

Microglial activation and neuroinflammation in the hippocampal CA1 region among the 4 groups. a Representative images of Iba1 (a marker of microglia) in the CA1 region. b Quantification of Iba1 fluorescence. c Representative Western blots of Iba1 among the 4 groups at day 1 after anesthesia/surgery. d Quantitative analysis of Iba1 levels compared with the control group. Analysis of TNF-α, IL-1β, and IL-6 levels in the hippocampal CA1 region on postoperative days 1 and 3 (eg and hj). The data are presented as the means ± standard error of the mean for each group (n = 6). *p < 0.05, **p < 0.01 compared with the C + VEH group, #p < 0.05 compared with the A/S + VEH group

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