Fig. 2

Fluoxetine reduced LPS-induced neuroinflammation. a Serum IL-1β, b serum IL-6, c serum TNF-α, d serum IL-10 level, e hippocampal IL-6, f hippocampal TNF-α, g hippocampal IL-10, h NLRP3 level column graph, and representative western blots for mice treated with LPS and fluoxetine. i Total level of caspase-1 and representative western blots. All the values were normalized with GAPDH. Image Lab Software was used for blots quantitative analysis and was analyzed via GraphPad prism. Data were expressed as ± SEM, one-way ANOVA followed by post hoc analysis. p = < 0.05 were considered significant. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001