Fig. 5

Fluoxetine attenuated LPS effect on mTOR/eEF2/BDNF/SNAP25/PSD95 and HDACs. a Representative immune blot images and average protein levels of b p-mTOR, c p-eEF2, d BDNF, e PSD95, f SNAP25, g 5HT2A, and h 5HT-2C. i–k Average level of HDAC1, HDAC2, and HDAC3 levels, respectively. l, m Golgi staining showing spine density and column graph showing spin numbers. Image Lab Software was used for blot quantitative analysis and was analyzed via GraphPad prism. Data were expressed as ± SEM, one-way ANOVA followed by post hoc analysis. p = < 0.05 were considered significant. *p < 0.05, **p < 0.01), ***p < 0.001, ****p < 0.0001