Fig. 6

LPS-mediated microglia activation uncouples transmembrane currents from [Ca²⁺]_i by reducing the functional expression of K_Ca3.1. Correlation plot linking the current potentiation to the Ca²⁺ transient amplitudes evoked by ATP in different experimental conditions. The solid line represents a linear regression constrained to pass through the point identified by the coordinates (0, 1). Please note that LPS treatment inhibits the current potentiation leaving unaltered the ability of ATP to increase [Ca²⁺]_i. Data represent mean values ± standard error mean. Bidirectional errors are shown, sometimes not visible due to error amplitude smaller than symbol dimensions