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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Transcriptome profiling of long noncoding RNAs and mRNAs in spinal cord of a rat model of paclitaxel-induced peripheral neuropathy identifies potential mechanisms mediating neuroinflammation and pain

Fig. 5

The validation of RNA-Seq dataset by means of qPCR and protein assays. a, b The expression of 5 randomly selected upregulated DEmRNAs (a) and 4 randomly selected downregulated DEmRNAs (b) from RNA-Seq dataset validated by qPCR. c The expression of some representative genes potentially involved in inflammation and pain response validated by qPCR. d, e The expression of 3 randomly selected upregulated DElncRNAs (d) and 2 randomly selected downregulated DElncRNAs (e) from RNA-Seq validated by qPCR. f ELISA test of CCL3 protein expression. g Western blot test of CXCL11 protein expression. n = 6 rats/group. *p < 0.05, **p < 0.01 vs. control group. Student’s t test was used for statistical analysis

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