Fig. 2

PEG-CeNP treatment reduced ROS accumulation and improved anatomical integrity of myelinated fibers after ICH. a Representative images in peri-hematoma site stained with the superoxide-sensitive dye DHE at 3 days post ICH. Lens: × 200; Scale bar: 100 μm. b Quantification of DHE+DAPI+ cells, n = 3/group, * p < 0.01 versus ICH + vehicle. c ROS levels in brain tissues at 3 days post ICH, n = 6/group, * p < 0.01 versus Sham, # p < 0.01 versus ICH + vehicle. d Representative electron micrographs showed myelin sheaths in striatum at 21 days post ICH. Lens: × 15,000; Scale bar: 2 μm. e Histograms show quantifications of the G-ratio at 21 days post ICH, n = 3/group, * p < 0.01 versus Sham, # p < 0.01 versus ICH + vehicle. f Scatter plots of G-ratio against axon diameter