Fig. 4

PEG-CeNP treatment-induced microglia skewed polarization after ICH. Representative RT-qPCR analysis of M2 (a–c) and M1 (d–f) microglia markers expression. n = 6/group, * p < 0.01 versus Sham. # p < 0.01 versus ICH 3d. ^ p < 0.01 versus ICH 7d. g Representative images of CD1632/Iba1 and CD206/Iba1 double immunostaining at 3 days post ICH. Lens: × 200; Scale bar: 100 μm. h CD16 mRNA expression in PEG-CeNP-treated mice at 3 days post ICH. n = 6/group, * p < 0.01 versus Sham, # p < 0.01 versus ICH + vehicle. i CD206 mRNA expression in PEG-CeNP-treated mice at 3 days post ICH. n = 6/group, * p < 0.01 versus Sham, # p < 0.05 versus ICH + vehicle. j Quantification of CD16/32⁺Iba1⁺ cells, n = 6/group, *p < 0.01 versus ICH + vehicle. k Quantification of CD206⁺Iba1⁺ cells, n = 6/group, * p < 0.05 versus ICH + vehicle