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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Can quantifying morphology and TMEM119 expression distinguish between microglia and infiltrating macrophages after ischemic stroke and reperfusion in male and female mice?

Fig. 5

Percent area of TMEM119 immunofluorescence is decreased in proximity to the infarcted tissue. a Images of IBA1 and TMEM119 immunofluorescence (× 20 objective) in the cortex of mice after sham and stroke procedure. Two brain regions (distal and proximal to injury) were imaged in the ipsilateral hemisphere. Below, cropped images show the detail, and composite show co-localization of IBA1 and TMEM119 immunofluorescence. b Illustration of brain regions imaged. c The percent area of IBA1 immunofluorescence per cells in the frame remains unchanged among brain regions and sex. d The percent area of TMEM119 immunofluorescence per IBA1 cells in the frame is decreased in the ipsilateral proximal region vs. sham in all sex groups. *p < 0.05; **p < 0.01. n = 6–9 in the sex groups and regions. Scale bar = 20 μm

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Journal of Neuroinflammation

ISSN: 1742-2094