Fig. 2

Motor impairments in neonates submitted to gestational sepsis. a, d For the cliff aversion test, offspring at P2 (a) and P8 (d) were positioned on the edge of the box and the total time that it took mice to turn away from the cliff and move away from the edge was recorded. Each bar is the mean +/− SEM from 3 litters with 10–12 offspring each. b, e The negative geotaxis assesses the motor coordination of animals at P2 (b) and P8 (e) by comparing the time to complete the test. Each bar is the mean +/− SEM from 3 litters with 10–12 offspring each. c, f The hindlimb suspension assesses the animal strength by recording their latency to fall at P2 (c) and P8 (f). Each bar is the mean +/− SEM from 3 litters with 10–12 offspring each. g, h The animals were subjected to the Rota Rod test to evaluate the motor ability in young (g) and adult (h) offspring from mothers submitted to gestational sepsis. Each bar is the mean +/− SEM from 3 litters with 10–12 offspring each. *p < 0.05 compared saline to sepsis. NS not significant