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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Presence and activation of pro-inflammatory macrophages are associated with CRYAB expression in vitro and after peripheral nerve injury

Fig. 3

Quantification of the number of pro-inflammatory and immunosuppressive macrophages in WT and Cryab−/− crushed sciatic nerves. Representative images and quantification of the number of CD16/32+ Iba1+ DAPI+ (a, c) and CD206+ Iba1+ DAPI+ (b, d) profiles in the sciatic nerves of naïve (N), and 3, 5, 7, 14, 21, and 28 days post-crushed WT (white bars) and Cryab−/− (black bars) animals; representative of 2 experiments, n=3–4 animals/group, bar = 20 μm, data represent mean ± sem, *p< 0.05 independent t-test. e Graph displaying the ratio of CD16/32+ cells to CD206+ cells for WT and Cryab/ nerves

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