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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Recombinant CCL17-dependent CCR4 activation alleviates neuroinflammation and neuronal apoptosis through the PI3K/AKT/Foxo1 signaling pathway after ICH in mice

Fig. 3

The effects of rCCL17 treatment on microglia/macrophage activation and neutrophil infiltration after ICH. a Representative images of immunofluorescence staining of Iba-1 (red), MPO (green), and IL-1β (green) in the perihematomal area at 72 h after ICH. b Brain sample with schematic illustration showing the area in the perihematomal region (indicated by white box) from where the images were taken for immunofluorescence staining. c Quantitative analyses of Iba-1, MPO and IL-1β positive cells in the perihematomal area at 72 h after ICH (n=4/group). d, e Representative western blot bands and quantitative analyses of Iba-1, MPO, and IL-1β protein levels at 72 h after ICH. *p<0.05 vs sham, @p<0.05 vs ICH + vehicle, mean ± SD, one-way ANOVA, Tukey test, n=6/group, scale bar=50 μm

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