Fig. 8
From: Recruitment of γδ T cells to the lesion via the CCL2/CCR2 signaling after spinal cord injury
Comparison of level of cytokines between TCRδ−/− mice reconstituted with CCR2−/− γδ T cells and TCRδ−/− mice transferred with WT γδ T cells at 1 day post-spinal cord injury (SCI). a Luminex analysis system (Bio-Rad, Hercules, CA) was used to analyze inflammatory protein level in spinal cord tissues at 1 day after SCI (n = 8 mice/per group). Different colors from low (blue) to high (red) represented the protein expression level (fold change). b Compared to WT γδ T cells reconstituted group, pro-inflammatory cytokines including TNF-α, IFN-γ, IL-1β, IL-1α, and IL-6, were significantly down-regulated and anti-inflammatory IL-10 was upregulated in CCR2−/− γδ T cells transferred group (n = 8 mice/per group). *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001