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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Pexidartinib treatment in Alexander disease model mice reduces macrophage numbers and increases glial fibrillary acidic protein levels, yet has minimal impact on other disease phenotypes

Fig. 3

Pexidartinib treatment does not increase body weight in AxD mice. Mice were weighed weekly beginning at treatment initiation (weaning, 3 weeks of age). Due to inherent differences in body weight, males and females were analyzed separately. Weight is expressed in grams (g). (a) Average male body weight. (b) Average female body weight. Statistical analyses: Two-way repeated measures ANOVA with Bonferroni’s post-test, *p<0.05, **p<0.01 comparisons between WT CON and AxD CON, †p<0.05, ††p<0.01 comparisons between AxD CON and AxD PEX. N = 10-14 per group

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Journal of Neuroinflammation

ISSN: 1742-2094