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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Fetal inflammation induces acute immune tolerance in the neonatal rat hippocampus

Fig. 7

Co-localization of M1 marker MHCII with Iba1+ microglia in the hippocampus at P7. Rat pups were exposed to prenatal i.a. LPS (L) or saline (S) (listed first) and then postnatal i.p. LPS or saline at P5 (listed second) to create four treatment groups. Total double positive Iba1 (green) and MHCII (red) cells were quantified in each treatment group (blue = DAPI). Bars above the graph indicate significant differences between groups (p < 0.05; n = 4–6/group). Data presented as mean ± SEM. Pictures representative of each group are shown at × 20. Scale bar represents 100 μm

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