The influence of BACE1 on macrophage recruitment and activity in the injured peripheral nerve

Table 1 Phenotypes of global BACE1 KO vs. macrophage specific BACE1 KO mice

Global BACE1 KO	Macrophage specific BACE1 KO
Hypomyelination at baseline [6, 34]	Normal myelination [70]
Enhanced axonal regeneration [8]	Not determined
Reduced remyelination [7]	Not determined
Enhanced macrophage recruitment [8]	No enhanced macrophage recruitment [70]

ISSN: 1742-2094