Skip to main content

Table 1 Markers of neurodegeneration strongly associated with inflammatory markers. Spearman’s correlation between inflammatory markers, IBA-1, TSPO, and C1q, measured by immunoreactivity and measures of neurodegeneration assessed by MRI volume and NeuN immunoreactivity in hippocampus (Hp) and cortex (Cx)

From: Neuroprotective effect of mitochondrial translocator protein ligand in a mouse model of tauopathy

Region

Inflammatory marker

Neurodegeneration marker

Correlation

r

p

Hp

IBA-1

MRI volume

-0.792

<0.0001

TSPO

-0.833

<0.0001

C1q

-0.538

0.005

IBA-1

CA1 Width

-0.679

<0.0001

TSPO

-0.772

<0.0001

C1q

-0.588,

0.002

Cx

IBA-1

MRI volume

-0.702

<0.0001

TSPO

-0.538

0.006

C1q

-0.795

<0.0001