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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Beyond the lesion site: minocycline augments inflammation and anxiety-like behavior following SCI in rats through action on the gut microbiota

Fig. 3

Minocycline treatment did not affect motor recovery in the open field or cylinder task. a Image showing a rat in the center of the open field apparatus. b Both SCI and SCI + minocycline groups traveled significantly less distance than uninjured rats in the open field at 7 days post-SCI. c The cylinder test was used to assess forepaw use asymmetry. d SCI resulted in decreased use of the ipsilesional paw compared to uninjured rats. Error bars represent the standard error of the mean. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Top asterisks represent the uninjured + minocycline groups vs. SCI (green) and SCI + minocycline (purple). Bottom asterisks represent uninjured vs. SCI (green) and SCI + minocycline (purple)

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