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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Mechanistic insights into the role of the chemokine CCL2/CCR2 axis in dorsal root ganglia to peripheral inflammation and pain hypersensitivity

Fig. 6

CCL2 release in DRG is not affected by chronic INCB3344 treatment. a, b Ipsilateral DRGs L4-L6 were extracted on day 10 post-CFA, after three daily i.t. injection of vehicle or 45 μg/kg INCB3344. Levels of CCL2 in the superfusate were determined by ELISA. Data in (b) correspond to the mean AUC ± SEM (n = 8 for each group) of CCL2 release on 11 collected fractions over 44 min after K+ stimulation (from 20 to 64 min). *P < 0.05; one-way analysis of variance followed by Bonferroni post-test

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