TY - JOUR AU - Suzuki, Kaoru AU - Shinohara, Mitsuru AU - Uno, Yoshihiro AU - Tashiro, Yoshitaka AU - Gheni, Ghupurjan AU - Yamamoto, Miho AU - Fukumori, Akio AU - Shindo, Akihiko AU - Mashimo, Tomoji AU - Tomimoto, Hidekazu AU - Sato, Naoyuki PY - 2021 DA - 2021/04/03 TI - Deletion of B-cell translocation gene 2 (BTG2) alters the responses of glial cells in white matter to chronic cerebral hypoperfusion JO - Journal of Neuroinflammation SP - 86 VL - 18 IS - 1 AB - Subcortical ischemic vascular dementia, one of the major subtypes of vascular dementia, is characterized by lacunar infarcts and white matter lesions caused by chronic cerebral hypoperfusion. In this study, we used a mouse model of bilateral common carotid artery stenosis (BCAS) to investigate the role of B-cell translocation gene 2 (BTG2), an antiproliferation gene, in the white matter glial response to chronic cerebral hypoperfusion. SN - 1742-2094 UR - https://doi.org/10.1186/s12974-021-02135-w DO - 10.1186/s12974-021-02135-w ID - Suzuki2021 ER -