Fig. 3

Association of sGFAP and sNfL with the EDSS. Association of sGFAP a and sNfL b with the Expanded Disability Status Scale (EDSS) score in AQP4-IgG+ (n = 33) and MOG-IgG+ (n = 16) patients. Results of linear models using log-transformed sGFAP and sNfL values adjusted for age and log-transformed time since last attack are shown below the plots. AQP4-IgG aquaporin-4 immunoglobulin G, β regression coefficient, CI confidence interval, effect size standardized effect size, MOG-IgG myelin oligodendrocyte protein immunoglobulin G, NMOSD neuromyelitis optica spectrum disorder, sGFAP serum glial fibrillary acidic protein, sNfL serum neurofilament light chain protein