Fig. 6

Infiltrates consist of large amounts of B cells. a Flow cytometry data of the cerebellum (absolute numbers) on days 0, 22, 33, and 60 show consistent findings with predominant CD19+ cells in the cerebellum of MOG-immunized GF-IL23 mice. In addition, CD4+ cells (d22, d60), CD8+ cells (d60), CD11b^highCD45^high (d33, d60), and also γδ TCR+ cells (d33) were elevated compared to WT mice. b Flow cytometry data of the myelon on day 22 and day 33 show elevation of CD4+ and CD19+ cells on d22 and CD19+ cells compared to WT mice. The mean value, standard deviation are given with *p < 0.05, **p< 0.01, ***p< 0.001 with n=5 transgenic/WT mice d0, n= 8–12 transgenic/WT mice d22, d33, and 6 transgenic/4 WT mice d60