Skip to main content

Table 2 Distribution of markers within the analytic sample (complete bispecimen data for both baseline and PO1MO, N = 29)

From: Plasma and cerebrospinal fluid inflammation and the blood-brain barrier in older surgical patients: the Role of Inflammation after Surgery for Elders (RISE) study

  

Data available at both BL and PO1MO

Time period

Biofluid

Mean ± SD

Median

Min

Max

Albumin (g/l)

    

 Baseline

CSF

0.18 ± 0.07

0.17

0.08

0.34

Plasma

28.64 ± 7.33

27.10

16.52

52.84

CSF/plasma ratio (× 10−3)

6.42 ± 2.62

6.64

2.31

14.20

 PO1MO

CSF

0.17 ± 0.06

0.17

0.07

0.34

Plasma

28.06 ± 7.48

27.25

18.97

57.11

CSF/plasma ratio (× 10−3)

6.42 ± 2.76

6.17

1.98

15.22

Interleukin-6 (pg/ml)

    

 Baseline

Plasma

3.67 ± 1.68

3.21

1.52

7.33

CSF

4.05 ± 1.58

3.49

1.31

8.67

 PO1MO

Plasma

5.41 ± 3.37

4.37

2.23

15.90

CSF*

3.91 ± 1.56

3.65

1.34

7.60

C-reactive protein (mg/l)

    

 Baseline

Plasma

7.41 ± 13.21

2.52

0.56

56.12

CSF

0.01 ± 0.01

0.01

0.00

0.07

 PO1MO

Plasma

8.18 ± 10.45

4.77

1.24

53.34

CSF

0.03 ± 0.04

0.01

0.00

0.17

Chitinase 3-like protein (ng/ml)

    

 Baseline

Plasma

96.76 ± 107.44

60.11

23.01

573.21

CSF

280.08 ± 62.46

286.47

131.11

378.19

 PO1MO

Plasma

135.68 ± 122.95

96.06

30.14

524.60

CSF

279.96 ± 61.30

292.23

142.02

396.58

  1. Abbreviations: CSF cerebrospinal fluid, PO1MO postoperative 1 month, SD standard deviation
  2. *Values for the outlier (> 130 pg/ml) removed (n = 28)