Skip to main content
Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Suppression of neuroinflammation by an allosteric agonist and positive allosteric modulator of the α7 nicotinic acetylcholine receptor GAT107

Fig. 2

Neuropathological features of spinal cords in EAE mice treated with GAT107. Spinal cords of mice from the placebo- and GAT107-treated groups were removed at day 30 after EAE induction. a Treatment with GAT107 (10 mg/day) for 8 days improved CNS inflammation and reduced the number of EAE lesions. Representative images (with hematoxylin and eosin staining) at × 20 magnification are shown for the b placebo- and c GAT107-treated cells. The arrows indicate the foci (n = 6 in the placebo group and n = 7 in GAT107-treated group) (**p < 0.001)

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094