Fig. 6From: Orthopedic surgery-induced cognitive dysfunction is mediated by CX3CL1/R1 signalingImpaired neurovascular coupling response to sensory stimulation in POCD. a Representative image of the intensity changes of the optical imaging signal during whisker stimulation. b Time course traces of relative changes in cerebral blood volume after stimulation. c Average of the maximum cerebral blood volume response (one-way ANOVA with Tukey’s post hoc test, n = 4 or 6 per group). Control, normal control group; TF2D, 2 days after tibial fracture surgery group; TF+Ab, 2 days after tibial fracture surgery group injected with neutralizing Ab. **p < 0.01 compared to the control; ##p < 0.01 compared to TF2DBack to article page