Fig. 3

TBI induces anxiety-like behavior in open-field test. a Representative trace plots from one mouse in each group during performance of an open-field test. b The time spent in the center during tests at indicated week (weeks − 1 and 0 were designated as the day prior to TBI and the date of TBI, respectively) was normalized to the baseline (prior to TBI). *p < 0.05 compared with the different points post-TBI in each group