Skip to main content
Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Conditional knockout of Tsc1 in RORγt-expressing cells induces brain damage and early death in mice

Fig. 7

A group of rare RORγt-positive cells with a high metabolic level exists in the mouse brain. a, b Relative expression of the RORγt mRNA in the whole brain and thymus (a) and RORγt protein expression in the whole brains (b) of mice at PNDs 14. c Proportion of RORγt-positive cells among total brain cells. d Functional enrichment analysis of the top 25% most highly expressed genes in RORγt-positive cells. e Functional gene sets identified by KEGG pathway enrichment analysis indicated increased metabolic pathway enrichment in RORγt-positive cells compared with RORγt-negative cells. Each dot represents one mouse, and error bars represent SEMs; ***p < 0.001. Unpaired two-tailed Student’s t test (a). Wilcoxon test (e)

Back to article page