Fig. 1
RNA sequencing data in a volcano plot and heatmap. a FPKM values of 11,617 detected genes were plotted in a volcano plot. The y-axis corresponds to the significance level represented with log10P value, and the x-axis displays the log2 (FC) value. The red dots represent the significantly (p < 0.05 and q < 0.05) upregulated genes in the ASD group; the blue dots represent the significantly (p < 0.05 and q < 0.05) downregulated genes in the ASD group. The dotted horizontal line means p = 0.05 [–log10 (1.30)]. b High expression genes are shown in red on the map; low expression genes are shown in green. The 117 up- and 83 downregulated DEGs were used to create the heatmap. ASD autism spectrum disorder, Ct control, DEGs differentially expressed genes, FC fold change