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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Acute inflammatory profiles differ with sex and age after spinal cord injury

Fig. 2

Younger mice have a higher proportion of MDMs at 7-DPI. Myeloid cells were isolated from the injured spinal cords of male and female, 4- and 14-MO mice at 7-DPI using a consistent gating strategy (Fig. 1a). a Representative flow plots of cells that were immuno-labeled for selection markers against all myeloid cells (CD45), phagocytic cells (CD11b), and neutrophils (Ly6G). b 4-MO mice presented with a larger proportion of MDMs compared to total phagocytic cells (p<0.05). Sample size include 4-MO female (n=3), 4-MO male (n=3), 14-MO female (n=3), and 14-MO male (n=2). Main effects were assessed using two-way ANOVA, followed by pairwise comparisons using Sidak’s for post hoc analysis when appropriate. All graphs present the standard error of measurement (SEM). *p<0.05

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