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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice

Fig. 10

The effects of Tβ4 intervention and inflammatory pathway inhibition on mice emotional performance. Diagrams of a elevated plus maze and d forced swimming test. b Entries and c time in open arms were recorded to assess anti-anxiety-like behavior. e Immobility duration were recorded to test depression-like behavior. The data are presented as mean ± SEM (n = 11–12/group). #p < 0.05, ###p < 0.001 vs WT mice; *p < 0.05 vs APP/PS1 mice

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