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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice

Fig. 8

The effects of Tβ4 intervention and inflammatory pathway inhibition on TNF-α expressing in neurons. Representative photomicrographs of NeuN+ and TNF-α+ cells in the a PtA and b hippocampus. The number of NeuN+ and TNF-α+ cells in c cortex and d hippocampus. The data are presented as mean ± SEM (n = 4/group) in the different experimental groups. #p < 0.05, ##p < 0.01 vs WT mice; *p < 0.05 vs APP/PS1 mice

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