Table 1 Demographics of all the study cases with or without global Aβ deposition
Group |  | gAβ - | gAβ + | p-value |
|---|---|---|---|---|
Sample size | Â | n = 14 | n = 16 | |
Age | range (years) | 66.21 – 79.53 | 67.37 – 79.63 |  |
mean ± SD | 75.83 ± 3.605 | 75.32 ± 3.708 | 0.821 | |
Sex | (F/M) | 6/8 | 9/7 | 0.715 |
PMI | range | 3 - 29 | 2.5 – 29.58 |  |
|  | mean ± SD | 11.56 ± 7.238 | 8.748 ± 7.803 | 0.07 |
Cogn global | mean ± SD | 0.4162 ± 0.3604 | 0.3103 ± 0.3535 | 0.423 |
Years of education | mean ± SD | 18.29 ± 3.832 | 17.56 ± 3.245 | 0.58 |
Apoe4 | Â | 0 | 5 (31.25 %) | 0.044 |
ApoE distribution | ε 2/2 | 0 | 0 |  |
ε 2/3 | 2 (14.28 %) | 2 (12.5 %) | ||
ε 2/4 | 0 | 0 | ||
ε 3/3 | 12 (85.71%) | 9 (56.25 %) | ||
ε 3/4 | 0 | 5 (31.25 %) | ||
ε 4/4 | 0 | 0 | ||
Braak score | 0 – II | 9 (64.29 %) | 7 (43.75 %) | 0.298 |
III - IV | 5 (35.71 %) | 9 (56.25 %) | ||
Braak score distribution | 0 | 1 (7.14 %) | 0 | Â |
I | 4 (28.57 %) | 4 (25%) | ||
II | 4 (28.57 %) | 3 (18.75 %) | ||
III | 4 (28.57 %) | 5 (31.25 %) | ||
IV | 1 (7.14 %) | 4 (25 %) | ||
V | 0 | 0 | ||
VI | 0 | 0 | ||
CERAD | possible or no AD | 14 (100 %) | 6 (37.5 %) | 0.0003 |
probable or definite AD | 0 | 10 (62.5 %) | ||
CERAD distribution | no AD | 13 (92.86 %) | 5 (31.25 %) | Â |
possible AD | 1 (7.14 %) | 1 (6.25 %) | ||
probable AD | 0 | 9 (56.25 %) | ||
definite AD | 0 | 1 (6.25 %) | ||
NIA-Reagan | low or no likelihood | 14 (100%) | 9 (56.25%) | Â |
intermediate/high likelihood | 0 | 7 (43.75%) | ||
NIA-Reagan distribution | no likelihood | 1 (7.14%) | 0 | 0.0073 |
low likelihood | 13 (92.85%) | 9 (56.25%) | ||
intermediate likelihood | 0 | 7 (43.75%) | ||
high likelihood | 0 | 0 | ||
p-tau | mean ± SD | 1.946 ± 2.31 | 1.274 ± 1.270 | 0.918 |
Aβ-IR | mean ± SD | 0 | 1.962 ± 1.946 |  |