Fig. 2

Effect of Ac2-26 on neurological function, cerebral infarct volume, and cortical CBF at 3 days post-tMCAO/R. a Schematic diagram of the experimental design. b–e Neurological function was evaluated by mNSS test (b), corner test (c), foot fault test (d), and adhesive removal test (e). f Representative photographs of nissl staining and quantitative analyses of cerebral infarct volume. g Representative photographs of laser speckle contrast imaging and quantitative analyses of cortical CBF. PU, perfusion unit. Data were presented as the mean ± SD (b–e n = 12/group; f–g n = 6/group) and were analyzed by independent samples t test. *p < 0.05, **p < 0.01, and ***p < 0.001