Fig. 7

Effect of Ac2-26-mediated microglia polarization on post-OGD/R HT22 neuronal apoptosis. a Schematic diagram of the experimental design. b Quantitative analyses of treated HT22 neuronal death using LDH release assay. c Representative photographs of immunostaining and quantitative analyses of HT22 neuronal apoptosis (TUNEL, green). Scale bar = 100 μm. d Representative western blotting bands and densitometric quantifications of cleaved-caspase-3. CL: cleaved. Data were presented as the mean ± SD (n = 6/group) and were analyzed by one-way ANOVA followed by Bonferroni's multiple comparison test. **p < 0.01, and ***p < 0.001, ^###p < 0.001