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Table 5 Comparison of gene expression between microglia isolated from the spinal cords of Cx43fl/fl and Cx43 icKO mice in the pre-immunized and peak phases of EAE

From: Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination

 

Cx43 fl/fl vs. Cx43 icKO

Gene cluster

Pre-immunized

Peak

Pro-inflammatory

0.0249 (fl/fl)

NS

Anti-inflammatory

0.0307 (icKO)

NS

Chemokines

0.017 (fl/fl)

NS

  1. Mouse genotypes showing significantly higher levels of the relevant gene expression than their comparators are indicated in parentheses. Peak is dpi 17
  2. Cx connexin, dpi days post-immunization, EAE experimental autoimmune encephalomyelitis, ES enrichment score, fl flox, icKO inducible conditional knock-out, NS not significant
  3. *P values of the ES plots are shown