Fig. 7
IL-1β neutralizing antibody failed to enhance heat intolerance under heat alone. Single dosages of 0.2 μg/g IL-1β neutralizing antibody were injected intravenously 30 min before heat stroke. Saline was involved in the control. a Core temperature (TC) profiles of mice were monitored in every 15 min to compare saline and IL-1β neutralizing antibody groups in the absence of prior infection. b Core temperature (TC) profiles of mice were monitored in every 15 min to compare saline and IL-1β neutralizing antibody groups with prior infection of LTA. The average time taken by core temperature to reach 42 °C was calculated as the mean ± SEM. (n = 5 to 10). **p < 0.01, nsp > 0.05 (ns: no significance)