Fig. 1
From: Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus
NanoString analysis demonstrates significant changes in gene expression with HFD. Male and female mice were fed control (Ctr) or high fat diet (HFD) for 14 weeks. A Hypothalami from 3 mice per group were dissected and the area containing the arcuate nucleus, and the median eminence from the 300-um coronal section was excised and 50 ng RNA used in NanoString analysis. Genes exhibiting significant changes in expression are highlighted with heat-maps. B The anterior portion containing POA and OVLT was excised and used in a separate NanoString neuroinflammation panel. Genes exhibiting significant changes in expression are listed