Fig. 2
From: Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus
Gene expression profile indicates neuroinflammatory changed in mice fed HFD. A A custom panel of 30 genes critical for hypothalamic function was included and several genes highlighted. B, C Highly regulated genes from the 770 gene off-the-shelf neuroinflammation panel are highlighted from the posterior sections (B) and anterior sections (C). The panel contains 7 housekeeping genes used for normalization and 8 genes to determine lower limit. The data analysis was performed using nSolver Analysis Software 4.0 and nCounter Advanced Analysis. Data were plotted as log fold change on x-axis vs. log p value on y-axis. Red indicates genes that increase with HFD compared to control fed mice, while green indicates genes that decease with HFD compared to controls