Fig. 3

GRb1 rescues neurogenesis impairment in hippocampus of mice exposed to CMS. (A) Immunohistochemistry for DCX and BrdU in DG. (B) The mRNA levels of DCX in DG area (n = 5 mice/group). (C, D) Number of BrdU⁺ or DCX⁺ cells in DG area. (E) Differentiation ratio of proliferative cells in DG. (F) DAPI-stained sections of DG and GCL, which were quantified by measure DG volume (G), GCL volume (H), and GCL thickness (I). Scale bars: 100 μm. Data are shown as mean ± SEM (n = 6 mice/group). The statistical results are shown in Table S4. *P < 0.05, ** P < 0.01, *** P < 0.001