Fig. 4

GRb1 activates PPARγ expression in CMS-induced depression model. (A, B) Relative mRNA levels of PPARа, PPARβ/δ, and PPARγ in hippocampus and cortex. (C, D) Representative western blot of p-PPARγ and PPARγ in hippocampus and cortex. (E, F) Quantification of PPARγ and p-PPARγ in hippocampus and cortex. (G, H) Representative western blot of p-PPARγ in nuclei of hippocampus and cortex. (I, J) Quantification of p-PPARγ in nuclei of hippocampus and cortex (n = 5 mice/group). The statistical results are shown in Table S5. *P < 0.05, ** P < 0.01, *** P < 0.001