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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Cordycepin confers long-term neuroprotection via inhibiting neutrophil infiltration and neuroinflammation after traumatic brain injury

Fig. 3

Effect of cordycepin on BBB integrity. a Representative images of a serial coronal sections of sulfo-NHS-biotin leakage on 3 days after TBI. Scale bar: 1 mm. b Quantification of sulfo-NHS-biotin leakage volume. n=7~9/group. c Representative images and 3D surface plot of IgG leakage on 3 days after TBI. Scale bar: 1 mm. d Quantification of IgG leakage area, intensity in CTX and STR. n=5/group. e Representative images of ZO-1 blot on 3 days after TBI. f Quantification of ZO-1 protein expression. n=4/group. g Representative transmission electron microscope images of BBB structure. Scale bar: 1 μm. h Representative images of MMP-2/9 blot on 24h and 3days after TBI. i Quantification of MM-2/9 protein expression. n=5/group. j Representative images of gelatin zymography. k Quantification of MMP-2/9 activity. n=6/group. ###p < 0.001 or *p < 0.05 as indicated

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