Skip to main content
Fig. 12 | Journal of Neuroinflammation

Fig. 12

From: Aging and high-fat diet feeding lead to peripheral insulin resistance and sex-dependent changes in brain of mouse model of tau pathology THY-Tau22

Fig. 12

Western blots of hippocampal tau protein de/phosphorylation enzymes of 11-month-old THY-Tau22 mice. a Western blots for specific proteins. b Quantification of (a) western blots. Data are presented as mean ± SEM and were statistically analyzed by Mann-Whitney t test within each age and sex group (*p < 0.05; **p < 0.01; n = 6). Mouse THY-Tau22 group on St diet was set as 100 %. The intensity of all proteins was related to particular β-actin intensity. The intensity of modified protein was related to the total protein. pERK1/2, extracellular signal-regulated kinase phosphorylated at T202/Y204 residues; PP2A C, C subunit of protein phosphatase 2A; met-PP2A C (L309), methylated C subunit of PP2A at L309 residue; pPP2A C (Y307), PP2A C phosphorylated at Y307 residue

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094