Skip to main content

Table 1 Experimental study design time course of THY-Tau22 and wt

From: Aging and high-fat diet feeding lead to peripheral insulin resistance and sex-dependent changes in brain of mouse model of tau pathology THY-Tau22

Age

  

3 months

7 months

11 months

Weeks on diet

0

1

6

8

22

23

24

37

38

42

Diet, treatment

St

St

Behavioral tests

Dissection after 12 h fasting

Diet, treatment

St

St/HF

OGTT after 6 h fasting

Behavioral tests

Dissection after 12 h fasting

Diet, treatment

St

St/HF

OGTT after 6 h fasting

Behavioral tests

Dissection after 12 h fasting

  1. Week 0 on diet corresponds to 7 weeks of age
  2. Abbreviations: HF high-fat diet, OGTT oral glucose tolerance test, St standard chow diet