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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner

Fig. 5

Microglia Ager deletion exerts sex-dependent effects on survival in SOD1G93A mice. a Kaplan–Meier estimates of percent of male mice surviving plotted vs. age (days). N = 16 SOD1G93A Agerfl/fl Cx3cr1Cre/+ mice, and N = 13 SOD1G93A Ager+/+ Cx3cr1Cre/+ mice. b Kaplan–Meier estimates of percent of female mice surviving plotted vs. age (days). N = 15 SOD1G93A Agerfl/fl Cx3cr1Cre/+ mice, and N = 14 SOD1G93A Ager+/+ Cx3cr1Cre/+ mice. The Logrank test was performed to compare the survival distributions between groups. *p = 0.0496

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