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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner

Fig. 7

Differential expression analysis between male SOD1G93A mice with microglia devoid of Ager and Cre-expressing controls. Volcano plot displaying differentially expressed genes between SOD1G93A Agerfl/fl Cx3cr1Cre/+ and SOD1G93A Ager+/+ Cx3cr1Cre/+ mice. The y-axis is –log10(p value) and x-axis is the Log2 fold change of each gene analyzed. Red colored genes are significantly differentially expressed with an FDR < 0.05. The top twenty significant genes are labeled. N = 4 independent mice/group

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Journal of Neuroinflammation

ISSN: 1742-2094