Fig. 3
From: Phloretin suppresses neuroinflammation by autophagy-mediated Nrf2 activation in macrophages
Phloretin activates AMPK. A, B Western blot quantification and representative bands of pAMPK and AMPK in LPS-activated BMDMs stimulated with phloretin or phloretin and the AMPK inhibitor BML-275 together (n = 3). The dotted line represents control cells stimulated with LPS. C ROS production in phloretin-treated or phloretin and AMPK inhibitor-treated BMDMs (n = 10). The dotted line represents control cells stimulated with PMA. Ctrl, control; phl, phloretin. Data are represented as mean ± s.e.m. *p < 0.05, **p < 0.01 and ***p < 0.001