Fig. 6
From: The potential roles of m6A modification in regulating the inflammatory response in microglia
Functional predictions of the hyper-upregulated mRNAs in M1-L versus M0-L based on pathway analysis. A–C Pathway analysis was applied to 9 mRNAs and revealed that 10 upregulated pathways were involved in 3 biological processes (P < 0.05). Enrichment scoring = −log10 (P value). D Nine m6A hyper-methylated mRNAs and their proteins are in the 10 upregulated signaling pathways. The green circles represent proteins, the orange arrows show the mRNA and protein pair, and blue arrows indicate signaling pathways that proteins involved. The mRNAs using red font represent the m6A mRNAs that were hypo-methylated in M2-L vs M1-L