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Table 2 Microglia activity, measured as cell body area/total cell area (%) in the different brain areas. C control, IBU ibuprofen. F statistics (F) are displayed for age (A), intervention (I), and age*intervention (A*I) effects. *p < 0.05

From: Acute pre-operative ibuprofen improves cognition in a rat model for postoperative cognitive dysfunction

 

Young

Aged

F-statistic

n

C

IBU

C

IBU

A

I

A*I

12

8

9

6

Brain area

 Prefrontal cortex

15.5 ± 1.2

15.8 ± 1.1

18.7 ± 0.8

20.5 ± 1.2

15.2*

ns

ns

 Striatum

12.0 ± 1.0

12.1 ± 0.6

15.6 ± 0.9

16.6 ± 0.9

18.5*

ns

ns

 Hypothalamus

13.1 ± 1.0

13.5 ± 1.6

18.0 ± 1.7

28.5 ± 0.9

12.6*

ns

ns

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Journal of Neuroinflammation

ISSN: 1742-2094